
Can life be reduced to chemistry? Or is it something more—something purposeful, holistic, and irreducible?

This short essay is based on one of my YouTube videos — a 3-minute philosophical reflection on the nature of life. It challenges the dominant reductionist view in biology and reintroduces a forgotten lineage of thought, stretching from Aristotle to Hans Driesch to my own theoretical work. It’s a call to rethink the biological sciences through a lens that embraces complexity, purpose, and form — rather than treating life as a mechanical accident of molecules.
This lineage is not a recent fashion. I first developed these ideas in 2016, in a paper that brought Aristotle and Driesch back to the center of biological thinking. What follows is a concise introduction to that older and deeper thread.
What is life?
Not metaphorically. Not poetically. But biologically — and philosophically.
For over a century, mainstream science has treated life as a byproduct of chemistry. The idea is simple: if you stir molecules long enough in a cosmic soup, life eventually “emerges”. But what if this assumption is not only inadequate — what if it is fundamentally flawed?
In the fourth century BCE, Aristotle proposed a revolutionary idea: that living beings are not simply matter in motion. They are animated by something he called psyche — not a soul in the modern mystical sense, but a principle of organization. In Aristotelian terms, form gives shape to matter. It’s what makes a body not just a heap of parts, but a unified, living whole.
This psyche is what distinguishes the living from the non-living. It’s what allows an organism to develop, heal, grow — to be a coherent something, not just an assembly of atoms.
Fast forward to the dawn of modern biology. In the early 20th century, German biologist Hans Driesch conducted a simple but astonishing experiment: he split a sea urchin embryo in half — and both halves developed into complete, viable larvae.
This result should not be possible if life were nothing but a mechanical sum of its parts. Something more must be guiding development from within. Driesch called this entelechy — an internal, organizing principle that drives the living toward a goal.
He was ridiculed by the scientific establishment. But his work remains a stark challenge to purely mechanistic biology.
In 2016, I (Dr. Agustín Ostachuk) revisited these ideas through both scientific and philosophical lenses. My thesis: life is not built up like a house from bricks. No matter how long you mix chemicals, a living organism will not emerge by accident.
Why? Because life is not an accidental assembly — it is a holistic form, a self-sustaining pattern of activity, what I call a teleological-purposeful formal agent.
These agents are neither mystical forces nor supernatural entities. They are immanent principles of biological organization — embedded within the living, guiding its development and behavior from within, toward specific ends.
From Aristotle’s psyche to Driesch’s entelechy and my own theory of teleological-purposeful formal agents, one idea remains constant:
This is not metaphysics dressed up as science. It’s a return to a richer, more coherent vision of biology — one that refuses to flatten life into lifelessness.
Perhaps it is time for a teleological revolution in the biological sciences — one that honors complexity without reducing it, one that sees life not as a mechanism, but as a purposeful whole.
The question is no longer whether life can be explained by physics and chemistry alone — but whether doing so causes us to miss the very essence of what life is.
Read the Full Article published in Ludus Vitalis in 2016: https://www.evolutio.ar/publications#The-Principle-of-Life-from-Aristotelian-Psyche-to-Drieschian-Entelechy
📺 Watch the video version of this essay here:
In the last few years, teleology and agency have returned to the center of biological debate. Books and articles now speak of organisms as goal-directed agents. This is welcome. But it is not new. This essay belongs to a lineage that began, in my case, in 2016, when I published a paper reconnecting Aristotle and Driesch with the problems of modern biology. The current conversation is catching up.
🧭 If this post inspired you, consider supporting EVOLUTIO on Patreon. This is part of a larger project exploring the philosophy of biology, the failures of mechanistic science, and the emergence of holistic, purpose-driven approaches to life.